28th November 2019 – Selecting a Spray Dryer for Development Studies and Clinical Manufacture

News 28th November 2019 – Selecting a Spray Dryer for Development Studies and Clinical Manufacture When customers initiate discussions with Upperton, one of the first questions we are asked is “which spray dryer(s) do you have and how much material can they produce?” Whilst these are very pertinent questions, the answer is not a simple … Read more

19th November 2019 – API Challenges in early stage formulation development, part 2

News 19th November 2019 – API Challenges during early formulation development, Part 2 There are many challenges that face companies taking a NCE into early stage feasibility testing and beyond. Some of these challenges are specific to the physical and chemical properties of the molecule in question (e.g. hard to handle API) whilst other challenges … Read more

Upperton continues to invest in key equipment to support expansion of its solid dosage form capabilities and CDMO Services

29th October 2019 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) has significantly increased its solid dosage form capabilities following a strategic investment in a new state-of the-art tablet coater. This investment will enhance the company’s development and manufacturing capabilities whilst strengthening their ability to support clients’ research, development … Read more

2nd October 2019 – API Challenges in Early Stage Formulation Development, Part 1

News 2nd October 2019 – API Challenges in Early Stage Formulation Development, Part 1 There are many challenges that face companies taking an NCE into early stage feasibility testing and beyond. Some of these challenges are specific to the physical and chemical properties of the molecule in question whilst other challenges are related to the … Read more

3rd September 2019 – Celebrating 20 years of pharmaceutical spray drying, 2nd Part

News 3rd September 2019 – Celebrating 20 years of pharmaceutical spray drying, part 2 Upperton celebrated their 20th anniversary on the 31st August and to mark the occasion we are releasing a two-part newsletter. Last week Upperton’s Founder and CEO Dr Richard Johnson talked about the company’s origins, what has driven the business success and … Read more

Developing Oral Dosage Forms for Clinical Trials

Producing a spray dried powder is rarely the end of developing oral dosage form pathway. Further processing is usually required in order to create a oral dosage form that can be administered in First-in-Human (FIH) or Proof of Concept (POC) clinical studies. The selection of a dosage form will involve a number of factors, for … Read more

19th March 2019 – Engineered Powders for Enhanced Pulmonary Delivery

News 19th March 2019 – Engineered Powder for Enhanced Pulmonary Delivery Upperton is continuing to invest in its combined spray drying and micronisation technology in order to meet increased demand. This emerging processing technology has been developed to enable the production of larger quantities of engineered powder formulations suitable for pulmonary delivery. The expansion of this service has … Read more