Nasal Inhalation Delivery – An Introduction Guide

An introduction to Nasal Delivery. The delivery of APIs via nasal inhalation is of growing interest to companies looking to exploit the benefits of this delivery route. Delivery targets are typically broken down into three categories Local delivery to the nasal membranes (e.g. for vaccines, antivirals, prophylactics) Systemic delivery by absorption into the bloodstream (e.g. … Read more

Nasally Delivered Dry Powder Dosage Forms: Particle Size Analysis

NEWSLETTER: Nasally Delivered Dry Powder Dosage Forms: Particle Size Analysis Introduction to Nasal Delivery The delivery of APIs via nasal inhalation is of growing interest to companies looking to exploit the benefits of this delivery route. Delivery targets are typically broken down into three categories Local delivery to the nasal membranes (e.g. for vaccines, antivirals, … Read more

In Vitro Testing of Dry Powder Nasal Delivery Devices

September 15th 2022 : Newsletter Successful nasal drug delivery of dry powder formulations requires a delivered dose that can penetrate beyond the nasal entrance region and deposit in the peripheral nasal cavity, whilst avoiding deeper penetration to the airways of the lungs. This delivery, or deposition pattern, is determined by the aerodynamic particle size of … Read more

Characterising the physical properties of spray dried powders

June 23rd 2022 : Newsletter The benefits of powder characterisation When developing products containing spray dried powders it is vital that the physical properties of the powders produced are determined. The physical properties of spray dried powders provides important information that can assist during the pre-formulation screening and early process development phases since these properties … Read more

Growing Interest in Nasal Delivery

Growing Interest in Nasal Delivery Recent trends have seen growing interest in exploiting nasal delivery as a means of delivering a wide range of drugs including small molecules and larger biologics for a wide range of indications. The nasal cavity is already a well-established delivery route capable of achieving rapid and high level of drug … Read more

29th April 2021 – Formulation Options in Nasal Drug Delivery

News 29th April 2021 – Formulation Options in Nasal Drug Delivery Nasal delivery offers a number of unique opportunities for the successful delivery of drugs and vaccines either locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to administer both therapeutic agents and vaccines via … Read more

Nasal Delivery of Therapeutics and Vaccines

The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to administer both therapeutic agents and vaccines via the nasal delivery … Read more

1st December 2020 – Manufacturing Clinical Supplies: The Early Phase Clinical Manufacture Timeline

News 1st December 2020 – Manufacturing Clinical Supplies: The Early Phase Clinical Manufacture Timeline Whilst undergoing research and development on a new chemical entity / new biological entity there are major initial objectives when planning the roadmap to clinic, submission and approval of the regulatory documentation, and ultimately dosage form administration in a human clinical … Read more

10th November 2020 – Manufacturing Clinical Supplies: Planning a First-in-Human Study

News 10th November 2020 – Manufacturing Clinical Supplies: Planning a First in Human Study Clinical trials are one of the most important components of any drug development project; requiring careful planning and extensive funding. Clinical trials are conducted to improve the efficacy and quality of a drug, to determine the dose and dose escalation, and … Read more

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