News Archives - Page 7 of 8 - Upperton Pharma Solutions

Using Spray Drying to Develop Inhaled Dosage Forms

May 14, 2025December 3, 2019 by admin_upperton

Pulmonary delivery is showing increased popularity as a viable dosage form for treating local airway diseases and offers additional potential for systemic drug delivery. Within this space there are a number of delivery approaches that can be undertaken. These include dry powder inhaled formulations (DPI) and pressurised metered Dose Inhalers (pMDIs). Each of these delivery … Read more

Selecting a Spray Dryer for Development Studies and Clinical Manufacture

June 16, 2025November 27, 2019 by admin_upperton

Talk to our experts Virtual Facility Tour When customers initiate discussions with Upperton, one of the first questions we are asked is “which spray dryer(s) do you have and how much material can they produce?” Whilst these are very pertinent questions, the answer is not a simple one. Selection of a spray dryer that is … Read more

API Challenges in early stage formulation development, part 2

November 4, 2024November 19, 2019 by admin_upperton

There are many challenges that face companies taking a NCE into early stage feasibility testing and beyond. Some of these challenges are specific to the physical and chemical properties of the molecule in question (e.g. hard to handle API) whilst other challenges are related to the embryonic stage of development that these molecules are in. … Read more

Upperton continues to invest in key equipment to support expansion of its solid dosage form capabilities and CDMO Services

October 17, 2024October 29, 2019 by admin_upperton

29th October 2019 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) has significantly increased its solid dosage form capabilities following a strategic investment in a new state-of the-art tablet coater. This investment will enhance the company’s development and manufacturing capabilities whilst strengthening their ability to support clients’ research, development … Read more

API Challenges in Early Stage Formulation Development, Part 1

November 4, 2024October 2, 2019 by admin_upperton

There are many challenges that face companies taking an NCE into early stage feasibility testing and beyond. Some of these challenges are specific to the physical and chemical properties of the molecule in question whilst other challenges are related to the embryonic stage of development that these molecules are in (e.g. limited API). When early stage … Read more

Upperton Pharma Solutions Investment Increases Tabletting Capabilities

October 16, 2024September 17, 2019 by admin_upperton

17th September 2019 – Press Release In recent weeks Upperton has been focussing heavily on enhancing our formulation capabilities (through increased tabletting capabilities) with a series of investments in new equipment for our R&D and QC laboratories. This is now being followed by our largest ever capital investment programme aimed at bringing in new manufacturing … Read more

10th September 2019 – Upperton Spray Drying Schedule: Autumn 2019

October 17, 2024September 10, 2019 by admin_upperton

The start of September is always a busy time in anyone’s calendar, whether you are a parent getting your children ready for school or a small CDMO looking to ramp up your development activities after the summer slowdown. Here at Upperton things are no different, September marks the start of what is traditionally one of … Read more

3rd September 2019 – Celebrating 20 years of pharmaceutical spray drying, 2nd Part

October 17, 2024September 3, 2019 by admin_upperton

Upperton celebrated their 20th anniversary on the 31st August and to mark the occasion we are releasing a two-part newsletter. Last week Upperton’s Founder and CEO Dr Richard Johnson talked about the company’s origins, what has driven the business success and how the industry has changed. In this week’s edition Richard Johnson looks forward and … Read more

Celebrating 20 years of pharmaceutical spray drying

October 16, 2024August 28, 2019 by admin_upperton

Celebrating 20 years of pharmaceutical spray drying Upperton will be celebrating its 20th anniversary on the 31st August 2019. Over this time Upperton has developed from a small consultancy business to become one of the world’s leading exponents of pharmaceutical spray drying services. To mark this occasion, we are publishing a special two-part newsletter. In … Read more

Developing Oral Dosage Forms for Clinical Trials – Tablets vs Capsules

March 17, 2025May 9, 2019 by admin_upperton

Dosage Form Selection Designing a Process for Tablet Manufacture Designing a Process for Capsule Manufacture FAQs Dosage Form Selection Producing a spray dried powder is rarely the end of developing an oral dosage form pathway. Further processing is usually required in order to create a oral dosage form that can be administered in First-in-Human (FIH) … Read more