By 2020, 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it has the potential to offer an alternative delivery method for therapeutics with some specific advantages. Nasal delivery of drugs has traditionally been via … Read more
Nasal Delivery Nasal Cavity Delivery to the Brain Fast Acting Absorption FAQs Overview of Nasal Delivery 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it holds the potential to offer an alternative delivery method … Read more
With the continued expansion of our tablet formulation development services, Upperton currently have a number of tablet dosage form development projects completed or in progress. Theses tablet / solid dosage form projects have encompassed a wide range of development activities from Active Pharmaceutical Ingredient (API) characterisation and feasibility studies through the application of enabling technologies, … Read more
29th April 2020 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) have invested £500K in significantly expanding their tablet manufacturing capabilities with the addition of tablet processing equipment for wet granulation, roller compaction, tablet compression, hardness testing, dedusting, weight sorting and tablet coating throughout 2019 and 2020. This investment … Read more
Stages of Tablet Compression Equipment Used During Formulation and Process Development Tablets are one of the most popular dosage forms used in the pharmaceutical, nutraceutical and veterinary industries due to their ease of handling and administration, stability, convenient packing options and well-established cost-effective manufacturing processes which produce consistent quality products. Developing a tablet formulation from … Read more
What Are ASDs? How Are ASDs Produced? Advantages of Spray Drying Challenges in Developing SDDs into Tablets FAQs Loading the Elevenlabs Text to Speech AudioNative Player… In this article, Upperton interviewed Dr Ian Lafferty, our Chief Technical Officer on the topic of developing spray dried dispersions (SDDs) into tablets. Ian has 25 years of technical … Read more
What is Granulation? Wet Granulation Wet Granulation Options Dry Granulation Dry Granulation Options Loading the Elevenlabs Text to Speech AudioNative Player… What is Granulation? Granulation has been widely used in the pharmaceutical industry since the 1950s. Whilst the science remains largely identical to that developed over 70 years ago, granulation techniques and equipment have improved … Read more
Tablet Formulation Strategies Solid Dosage Forms Tablet Manufacture Process Tablet Press FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Tablets continue to be one of the most popular pharmaceutical dosage forms, as with the right tablet formulation you can achieve: ease of handling and administration for patients, stability convenient packing options, and well-established cost-effective … Read more
What are Oral Solid Tablets? Examples of Tablets Considerations for Tablet Design FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Tablet dosage forms are one of the most popular dosage forms used in the pharmaceutical industry due to their ease of handling and administration for patients, stability, convenient packing options and well-established cost-effective manufacturing … Read more
The number of amorphous solid dispersions entering first in human (FIH) studies continues to increase, due to the growing number of novel APIs with a poor solubility profile, and associated bioavailability challenges. Spray drying is a useful technology for creating a form of amorphous solid dispersions called spray dried dispersions (SDDs). Spray drying a poorly … Read more
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