Liquid Delivery Dry Powder Delivery Dry Powder vs Liquid Devices Delivery Considerations FAQs Nasal delivery options The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in growing … Read more
Overview of Nasal Delivery Nasal Physiology for Drug Delivery Nasal Delivery Advantages FAQs Nasal Delivery Overview The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in … Read more
Early Phase Timeline Formulation Development Excipient Compatibility Clinical Manufacture FAQs An Overview of Early Phase Clinical Manufacture Clinical trials are a critical step in pharmaceutical development, ensuring the safety and efficacy of new treatments before they reach patients. They involve a series of rigorously designed phases with specific objectives and regulatory requirements. Small pharma companies … Read more
What are Clinical Trials? What is a First in Human Study? Proof of Concept FIH Studies Commercial Robust Method FAQs What are Clinical Trials? Clinical trials are one of the most important components of any drug development project, requiring careful planning and extensive funding. Clinical trials are conducted to improve the efficacy and quality of … Read more
Manufacturing a suitable placebo dosage form presents many unique challenges over and above those required for the active product.
Nasal Delivery The Nasal Cavity Nasal Devices Patient Profile Target Dose FAQs Nasal delivery overview Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route offers a range of advantages including its relative ease of use as compared to injectable … Read more
By 2020, 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it has the potential to offer an alternative delivery method for therapeutics with some specific advantages. Nasal delivery of drugs has traditionally been via … Read more
Nasal Delivery Nasal Cavity Delivery to the Brain Fast Acting Absorption FAQs Overview of Nasal Delivery 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it holds the potential to offer an alternative delivery method … Read more
With the continued expansion of our tablet formulation development services, Upperton currently have a number of tablet dosage form development projects completed or in progress. Theses tablet / solid dosage form projects have encompassed a wide range of development activities from Active Pharmaceutical Ingredient (API) characterisation and feasibility studies through the application of enabling technologies, … Read more
29th April 2020 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) have invested £500K in significantly expanding their tablet manufacturing capabilities with the addition of tablet processing equipment for wet granulation, roller compaction, tablet compression, hardness testing, dedusting, weight sorting and tablet coating throughout 2019 and 2020. This investment … Read more
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