Overview of Nasal Delivery Nasal Physiology for Drug Delivery Nasal Delivery Advantages FAQs Nasal Delivery Overview The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in … Read more
Early Phase Timeline Formulation Development Excipient Compatibility Clinical Manufacture FAQs An Overview of Early Phase Clinical Manufacture Clinical trials are a critical step in pharmaceutical development, ensuring the safety and efficacy of new treatments before they reach patients. They involve a series of rigorously designed phases with specific objectives and regulatory requirements. Small pharma companies … Read more
What are Clinical Trials? What is a First in Human Study? Proof of Concept FIH Studies Commercial Robust Method FAQs What are Clinical Trials? Clinical trials are one of the most important components of any drug development project, requiring careful planning and extensive funding. Clinical trials are conducted to improve the efficacy and quality of … Read more
Manufacturing a suitable placebo dosage form presents many unique challenges over and above those required for the active product.
Nasal Delivery The Nasal Cavity Nasal Devices Patient Profile Target Dose FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour Nasal delivery overview Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route … Read more
By 2020, 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it has the potential to offer an alternative delivery method for therapeutics with some specific advantages. Nasal delivery of drugs has traditionally been via … Read more
With the continued expansion of our tablet formulation development services, Upperton currently have a number of tablet dosage form development projects completed or in progress. Theses tablet / solid dosage form projects have encompassed a wide range of development activities from Active Pharmaceutical Ingredient (API) characterisation and feasibility studies through the application of enabling technologies, … Read more
Stages of Tablet Compression Equipment Used During Formulation and Process Development Tablets are one of the most popular dosage forms used in the pharmaceutical, nutraceutical and veterinary industries due to their ease of handling and administration, stability, convenient packing options and well-established cost-effective manufacturing processes which produce consistent quality products. Developing a tablet formulation from … Read more
What Are ASDs? How Are ASDs Produced? Advantages of Spray Drying Challenges in Developing SDDs into Tablets FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour In this article, Upperton interviewed Dr Ian Lafferty, our Chief Technical Officer on the topic of developing spray dried dispersions (SDDs) into … Read more
What is Granulation? Wet Granulation Wet Granulation Options Dry Granulation Dry Granulation Options Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour What is Granulation? Granulation has been widely used in the pharmaceutical industry since the 1950s. Whilst the science remains largely identical to that developed over 70 years … Read more
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