23rd May 2022 : Press Release Upperton Pharma Solutions (Upperton), a UK-based specialist contract development and manufacturing organisation (CDMO), has announced a circa. £15m investment into the design and build of a 50,000 sq ft facility in Nottingham. The new facilities will allow a significant increase in research and development laboratory space and a 10-fold … Read more
21st April 2022 – Press Release Inflexion is pleased to announce it has made a substantial investment into Upperton Pharma Solutions (“Upperton”), a UK-based specialist contract development and manufacturing organisation (“CDMO”) which has expertise in particle engineering for the pharmaceutical industry. Inflexion has invested alongside the founder and the management team who will continue to … Read more
5th April 2022 – Press Release Nottingham-based contract development and manufacturing organisation (CDMO), Upperton Pharma Solutions, has launched a unique nasal delivery development platform, UpperNose™, to make it easier and faster for small and mid-sized innovators to access the knowledge and capabilities necessary for the successful development of nasal dosage formulations. Drug developers seeking to … Read more
The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to administer both therapeutic agents and vaccines via the nasal delivery … Read more
Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route offers a range of advantages including its relative ease of use as compared to injectable administration, patient acceptability and compliance. It also provides a suitable route for those compounds that … Read more
Stages of Tablet Compression Equipment Used During Formulation and Process Development Tablets are one of the most popular dosage forms used in the pharmaceutical, nutraceutical and veterinary industries due to their ease of handling and administration, stability, convenient packing options and well-established cost-effective manufacturing processes which produce consistent quality products. Developing a tablet formulation from … Read more
Oral Solid Dosage Forms Containing Amorphous Spray Dried Dispersions: Choices for First in Human Studies The number of amorphous solid dispersions entering first in human (FIH) studies continues to increase, due to the growing number of novel APIs with a poor solubility profile, and associated bioavailability challenges. Spray drying is a useful technology for creating … Read more
10th December 2019 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) are launching an enabling technology screening protocol which aims to support companies with the rapid development of both standard and complex drug products. The new enabling technology screening protocol, integrates the company’s existing formulation capabilities with a biopharmaceutical … Read more
Pulmonary delivery is showing increased popularity as a viable dosage form for treating local airway diseases and offers additional potential for systemic drug delivery. Within this space there are a number of delivery approaches that can be undertaken. These include dry powder inhaled formulations (DPI) and pressurised metered Dose Inhalers (pMDIs). Each of these delivery … Read more
17th September 2019 – Press Release In recent weeks Upperton has been focussing heavily on enhancing our formulation capabilities (through increased tabletting capabilities) with a series of investments in new equipment for our R&D and QC laboratories. This is now being followed by our largest ever capital investment programme aimed at bringing in new manufacturing … Read more
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