Upperton Launches ASAPprime® Shelf-Life Stability Testing

November 16th 2022 : Newsletter Upperton has made a significant investment in ASAPprime® software and hardware to enable the company to offer its clients state of the art stability testing. This exciting new platform can be used to generate robust, accelerated chemical stability data and is now being applied at all stages of the product … Read more

Inflexion announces investment into Upperton

21st April 2022 – Press Release Inflexion is pleased to announce it has made a substantial investment into Upperton Pharma Solutions (“Upperton”), a UK-based specialist contract development and manufacturing organisation (“CDMO”) which has expertise in particle engineering for the pharmaceutical industry. Inflexion has invested alongside the founder and the management team who will continue to … Read more

20th May 2021 – Upperton Nasal Delivery Article Published in ONdrugDelivery

Article 20th May 2021 – Upperton Nasal Delivery Article Published in ONdrugDelivery Formulation Options In Nasal Drug Delivery Upperton had an article published in Edition 119 ONdrugDeliver in May 2021 In the article Richard Johnson, CEO and founder of Upperton,  discusses the advantages of nasal delivery and why there is growing interest in this route … Read more

29th April 2021 – Formulation Options in Nasal Drug Delivery

News 29th April 2021 – Formulation Options in Nasal Drug Delivery Nasal delivery offers a number of unique opportunities for the successful delivery of drugs and vaccines either locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to administer both therapeutic agents and vaccines via … Read more

25th March 2021 – Formulation Options in Nasal Drug Delivery

News 25th March 2021 – Formulation Options in Nasal Drug Delivery The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to … Read more

Nasal Delivery of Therapeutics and Vaccines

The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in growing interest from scientists looking to administer both therapeutic agents and vaccines via the nasal delivery … Read more

1st December 2020 – Manufacturing Clinical Supplies: The Early Phase Clinical Manufacture Timeline

News 1st December 2020 – Manufacturing Clinical Supplies: The Early Phase Clinical Manufacture Timeline Whilst undergoing research and development on a new chemical entity / new biological entity there are major initial objectives when planning the roadmap to clinic, submission and approval of the regulatory documentation, and ultimately dosage form administration in a human clinical … Read more

10th November 2020 – Manufacturing Clinical Supplies: Planning a First-in-Human Study

News 10th November 2020 – Manufacturing Clinical Supplies: Planning a First in Human Study Clinical trials are one of the most important components of any drug development project; requiring careful planning and extensive funding. Clinical trials are conducted to improve the efficacy and quality of a drug, to determine the dose and dose escalation, and … Read more

27th October 2020 – Manufacturing Clinical Supplies: The Role of Placebos and the Challenges of Manufacturing they Present

News 27th October 2020 – Manufacturing Clinical Supplies: The Role of Placebos and the Challenges of Manufacturing they Present One aspect of clinical trial manufacturing that often slips under the radar when designing, planning, and budgeting a clinical study is the role and supply of the placebo control. A placebo is defined as a substance … Read more

Key Considerations when Choosing a Device for Dry Powder Nasal Delivery

Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route offers a range of advantages including its relative ease of use as compared to injectable administration, patient acceptability and compliance. It also provides a suitable route for those compounds that … Read more

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