Formulation
Development.
Overcoming poor solubility and bioavailability challenges.
We have extensive formulation development experience taking research projects from early proof of concept and feasibility through scale-up and onto clinical manufacture for a range of dosage forms.
Collaborative and science-led
Our approach to formulation development.
We work closely with clients from the start, defining project aims and understanding the target product profile. Early development includes pre-formulation activities and excipient selection to create the ideal dosage form. Throughout, we focus on formulation suitability, scale-up potential, and commercialization. Stability studies and extensive analytical techniques ensure product quality.
Once a formulation is ready, we scale the process in our pilot plant, equipped to mirror our GMP facility, ensuring confidence before clinical manufacture.
Expertise
Our Leadership team has extensive collective experience in steering products from pre-clinical to commercial manufacture.
Science-led
Our approach is scientific, collaborative and open, ensuring an open dialogue and transparency that fits your project.
Award-winning
We are a leading CDMO recognised for numerous awards including a King's Award For Enterprise.
Nimble
We adapt to your project needs, and pledge to never relegating it to the bottom of the list.
Dosage Form Development
Experts in oral, nasal and pulmonary formulation development.
Oral dosage forms
- Blending, dry granulation, milling, coating
- Tablets (IR, MR, SR, Minitabs)
- Capsules (API, Powder blend, lipid)
- Small molecules, biologics, NCEs
- Grams to 250Kg batch sizes
Nasal and Pulmonary dosage forms
- (Nasal) Powder and liquid dosage forms
- (Pulmonary) powder
- Spray drying intermediates, micronization, lipids
- Capsule filling, device filling
- Blister packaging
Pharmaceutical Spray Drying
Overcoming poor solubility and bioavailability formulation challenges.
We’re specialists in the use of pharmaceutical spray drying to improve the solubility and bioavailability of your formulation, helping to enhance the dissolution rate and stability.
UpperSolv™ development platform
Identifying a successful formulation strategy.
Our early formulation platform, UpperSolv™ outlines a parallel integrated formulation and biopharmaceutical screening protocol that can rapidly compare a range of enabling formulation strategies that can be translated into clinical processes and products.
Frequently Asked Questions
What is pharmaceutical spray drying, and how does it work?
Pharmaceutical spray drying is a process that converts a liquid solution or suspension into a dry powder form. It involves atomizing the liquid into fine droplets and then rapidly drying these droplets by exposing them to a stream of hot air or gas, causing the solvent to evaporate and leaving behind solid particles.
What are the advantages of using spray drying in pharmaceutical formulations?
Spray drying offers several advantages in pharmaceutical formulations, including precise control over particle size and distribution, improved solubility of poorly soluble drugs, enhanced bioavailability, ease of scale-up, and versatility in producing various dosage forms such as powders, granules, and microspheres.
What types of pharmaceutical products can be produced using spray drying?
Pharmaceutical spray drying can be used to produce a wide range of products, including inhalable powders for pulmonary and nasal delivery, solid dispersion systems (SDDs) to improve drug solubility, modified release formulations for controlled drug release, and stable formulations of biologics.
Get in touch
If you’re looking to work with a CDMO that is flexible and nimble, then we’re here to help.
