Characterisation of Spray Dried Biologics

This whitepaper explores how spray drying can be used to create dry powders containing small molecules and much larger, more complex molecular structures such as biologics. These dry powder biologics require more complex assay techniques than those typically used for dosage forms containing small molecule APIs

Whitepaper Contents.

• An overview of how spray drying has evolved from oral small molecule delivery to broader applications

• Insights into the use of spray drying for formulating complex biologics, including peptides, antibodies, and vaccines

• Discussion of the unique challenges involved in spray drying biologics

• Identification of critical analytical techniques for assessing biologic structure and stability

• Guidance on selecting assays to evaluate physical, chemical, and functional attributes

• Strategies for maintaining functional activity of biologics after spray drying and during storage

• Practical considerations for developing robust, stable spray-dried biologic formulations