+44 (0)115 855 7050 enquiry@upperton.com

About Upperton

Experts in spray drying and formulation development

Founded in 1999, Upperton Pharma Solutions have a long track record in overcoming complex formulation challenges, and taking products from early feasibility batches to Phase II and beyond.

Our primary focus has always been on the versatile technology of spray drying and we have built up the expertise to support even the most challenging of molecules.

From our R&D labs and pilot plant facility in Nottingham, our experienced team of scientists work to deliver spray drying and formulation development services, to pharmaceutical and biotech companies throughout the world.

Our services include:

  • A comprehensive spray drying service: From bench top production of milligram-scale feasibility batches to kilogram-scale production in our pilot plant
  • Full pharmaceutical development service: Including pre-formulation screening formulation and final dosage form development.
  • Extensive physical and chemical characterisation of in-process and finished products
  • GMP spray drying and clinical dosage for manufacture and associated regulatory/analytical support
  • Richard Johnson

    Richard Johnson

    Founder and CEO

    Dr Richard Johnson founded Upperton Pharma Solutions in August 1999, and continues to play a key role in the management and strategic development of the company. With over 30 years of experience in the pharmaceutical, biotechnology and drug delivery fields, Richard previously held senior management positions at Andaris Limited (Vectura) and Delta Biotechnology (now Albumedix). Richard holds an honours degree in Biology from University of York and a Ph.D. from the University of Warwick and has a proven track record in successfully developing innovative pharmaceutical products from early feasibility studies through to commercial products.

  • Karen Coombes

    Karen Coombes

    Commercial Director

    Karen Coombes joined Upperton Pharma Solutions as Operations Director in 2008, having previously held positions at Advanced Protein Systems, Andaris Limited (Vectura) and Unilever Research. Karen holds an honours degree in Chemistry from the University of Bath and a master’s degree in Biotechnology from the University Of Nottingham and has a wealth of experience in the pharmaceutical and biotechnology industry. Karen is responsible for scale up projects and for directing all non GMP manufacturing activities in the company's pilot plant.

  • Andrew Naylor

    Andrew Naylor

    R&D Director

    Dr Andrew Naylor was appointed R&D Director for Upperton Pharma Solutions in August 2015, having previously held the position of Head of Process Development at Critical Pharmaceuticals. Andrew holds a Masters and PhD degrees in Chemistry from the University of Nottingham. Andrew has extensive experience in the development and analysis of pharmaceutical products and has sat on several Royal Society of Chemistry special interest group committees in the fields of polymer and materials science. Andrew is responsible for directing all of our research and development activities.

  • Paul Kelsall

    Paul Kelsall

    Director of Clinical Trials Manufacturing

    Paul Kelsall joined Upperton Pharma Solutions in August 2018. Paul has over 20 years of experience in the pharmaceutical industry, having previously worked for Boots, Reckitt Benckiser, Nova Laboratories and Aesica. Paul's experience covers both Sterile and Non-Sterile Manufacturing, Formulation Development, Facilities Management and Business Improvement. Paul's responsibilities include managing the Upperton Pharma Solutions Facility and all the GMP Operations that are conducted on site. Paul is also responsible for the New Business Introduction of all GMP projects.

  • Sarah Bayliss

    Sarah Bayliss

    Director of Quality & Compliance

    Sarah Bayliss joined Upperton in December 2017 as Director of Quality and Compliance. Her previous roles include Corporate QA Operations Manager, Head of Quality, Technical Manager and General Manager for pharmaceutical and medical device businesses within the manufacturing areas of Europe and the USA. Sarah has over 20 years’ experience of implementing, maintaining and remediating Quality Management Systems, working under MIA, IMP, MS and WD licences. Sarah is responsible for ensuring that Upperton Pharma Solutions are compliant and that our Quality Management Systems are implemented and adhered to in-line with the site relevant licensing activities (GMP) under MHRA & FDA regulations.

  • Laura Mason

    Laura Mason

    Director of Business Operations

    Dr Laura Mason joined Upperton in 2016 as a Project Scientist, quickly progressing to the role of Business Operations Director. Laura has previous experience within solid oral dosage form development having completed her PhD in the School of Pharmacy at the University of Nottingham, and her Pharmacy Pre-Registration Year at Merck Sharp and Dohme and Guy’s & St Thomas’ Hospital. Laura is a UK Registered Pharmacist, the current treasurer of the UKICRS and a member of several pharmaceutical societies. Laura supports the introduction and co-ordination of the company's R&D projects.

  • Thomas Williams

    Thomas Williams

    Head of Clinical Manufacturing

    Thomas Williams joined Upperton Pharma Solutions at Easter 2018. Thomas has an honours degree in Biochemistry and Molecular Biology, from the University of Sheffield. He is a member of the Royal Society of Biology, and has over 10 years’ experience in developing and manufacturing investigational medicinal products for Phase I and II clinical trials. His main responsibilities include management of the Controlled Cleanroom facility and overseeing GMP manufacturing activities.

  • Shailesh Mistry

    Shailesh Mistry

    Senior Scientist

    Shailesh Mistry joined Upperton in July 2017 as a Senior Scientist. Shailesh is a Medical Sciences graduate from the University of Birmingham, with over 15 years’ experience in the pharmaceutical industry. Before joining Upperton, he held senior scientist positions at Co-Formulate, Omniceutica and Vectura and has worked on wide range of pharmaceutical development projects from early feasibility stage through to full scale GMP manufacture. Shailesh is responsible for managing research and development projects.

  • Rebecca Gray

    Rebecca Gray

    Senior QC Analyst

    Rebecca Gray joined Upperton in August 2018 as Senior QC analyst. Rebecca has gained a master’s degree in Chemistry from the University of Sheffield and has been working within the pharmaceutical industry for 5 years in various analytical roles gaining experience in QC testing, early formulation development analysis and analytical method qualification. Key responsibilities are to support the setting up of the new QC laboratory and undertake QC testing of drug formulations prepared in the GMP manufacturing suite.

  • Richard Johnson
  • Karen Coombes
  • Andrew Naylor
  • Paul Kelsall
  • Sarah Bayliss
  • Laura Mason
  • Thomas Williams
  • Shailesh Mistry
  • Rebecca Gray

About Us

With over 20 years of experience we have successfully spray dried, formulated and characterised a vast range of pharmaceutical and biotechnology products for companies across the globe.


Contact Us

Would you like to find out more about our services or how we can help advance your project?


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- Address

Upperton Pharma Solutions,
Albert Einstein Centre,
Nottingham Science & Technology Park,

- Contact
+44 (0)115 855 7050