Poster overview
Scaling spray-dried nasal powders from development to commercial manufacture can be challenging, particularly when maintaining the particle characteristics required for effective nasal delivery. This study demonstrates how selecting the right atomisation technology can enable successful scale-up while preserving critical powder attributes and performance.
Key Takeaways
- Demonstrated successful scale-up of a spray-dried nasal powder from lab to commercial scale.
- Atomisation nozzle selection was the key factor influencing particle size and powder quality.
- Ultrasonic and pressure nozzles produced particles better suited for nasal delivery.
- Optimised powders showed improved flowability, supporting efficient manufacturing and device filling.
- Provides a practical strategy for developing scalable nasal dry powder products.
Download the poster to discover how spray drying and particle engineering can support the successful development and scale-up of nasal drug products.