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Transitioning from Phase I to Phase II
Our guide on Phase I outcomes and next steps
Learn more →High Potency & Schedule I-IV
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Formulating And Delivering Psychedelics
A CDMO's View On The Possibilities Of Psychedelics
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Rapid tech transfer to clinical manufacture
Read how we reached clinical dosing within three months, through strong communication, flexibility and responsiveness.
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Why Spray Drying Is Gaining Attention as a Biologics Lifecycle Management Strategy
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Get in touch
Call +44 (0) 115 855 7050
Visit: Trent Gateway, Technology Drive, Beeston, Nottingham, NG9 1LA
Discover the milestones that have shaped the company we have become today.
Upperton Limited was formally established on August 31st, 1999.
Dr. Richard Johnson, co-founder of the drug delivery company Andaris, initiated the company’s inception. Initially operating as a consultant under the Upperton Limited name, Dr. Johnson provided specialised technical consultancy services centred on spray drying and cleanroom technology, catering to clients across the UK and Europe.
The establishment of GMP facilities at the Albert Einstein Centre, Nottingham, in 2018, and a successful MHRA accreditation, marked a significant milestone in Upperton’s journey, solidifying its status as a GMP-certified entity committed to upholding the highest standards of quality and compliance.
In 2022, Upperton Pharma Solutions received significant development capital investment from Inflexion, signalling a new era of growth and expansion for the company.
Over the coming year, the headcount increased from 40 to 90 employees with an influx of pharmaceutical talent, alongside a significant expansion in its scale and capabilities through investment in state-of-the-art equipment.
In January 2023 the build of a new 50,000 sqft development and manufacturing facility in Beeston, Nottingham started.
The facility benefited from a £20 million investment in commercial scale equipment, offering powder blending up to 250kg per batch, capsule filling up to 40,000 capsules/hour, dry granulation processing up to 100kg/hour, and tablet pressing up to 120,000 tablets/hour.
In August 2023, Upperton was honored with the King’s Award for Enterprise in International Trade, marking a notable achievement.
This recognition reflects Upperton’s remarkable growth since 2020 and its dedication to enhancing global partnerships within the pharmaceutical sector.
In October 2023, the Trent Gateway facility construction was successfully finished in an unprecedented timeframe of just 10 months.
This achievement marks a significant milestone for Upperton, providing a substantial increase in manufacturing footprint from 1,300 sq.ft. to 13,000 sq.ft., along with a notable expansion of analytical laboratory space from 880 sq.ft. to 8,500 sq.ft.
The new site supports early formulation development, clinical trial supplies ranging from Phase 1 to Phase 3, and niche-scale commercial manufacturing.
The culmination of Upperton’s journey thus far was celebrated with the official opening of Trent Gateway as the ‘The Richard Johnson Building’ in April 2024, serving as a testament to the company’s resilience, innovation, and unwavering commitment to excellence.
In September 2026, Upperton announced that the Medicines and Healthcare products Regulatory Agency (MHRA) had approved a variation to its existing Manufacturing and Importation Authorisation for Investigational Medicinal Products (MIA(IMP)) licence, extending its scope to include the company’s new Annex 1-aligned sterile manufacturing facility at Trent Gateway, Nottingham.




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