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Selecting your CDMO partner.

Why Upperton is the specialist CDMO for molecules that demand more.

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your integrated cdmo

Transforming complex molecules into manufacturable medicines.

The most challenging drug products rarely follow a standard pathway.

Poor solubility. Low bioavailability. Complex delivery requirements. Limited API availability. Aggressive timelines.

At Upperton, we help pharmaceutical and biotech companies overcome these challenges through integrated CDMO services that connect formulation development, analytical science, clinical manufacturing and regulatory support within a single programme team.

From early feasibility through to clinical supply, we provide the scientific expertise, operational agility and manufacturing capability needed to move programmes forward with confidence.

“When faced with a molecule that needed to transition from candidate nomination to first-in-human trials within 10 months, Upperton’s deep expertise in navigating these kinds of challenges made them the clear choice. The Upperton team brought genuine curiosity and relentless focus to every stage of the development journey in order to deliver.”
Head of CMC
GreyWolf Therapeutics

beyond a traditional cdmo

More than a CDMO. We're a strategic partner.

Successful drug development depends on more than manufacturing capability.

It requires scientific understanding, proactive project leadership and the ability to identify risks before they become delays.

Our multidisciplinary teams work as an extension of yours, bringing together formulation scientists, analytical experts, manufacturing specialists, quality professionals and project managers to deliver coordinated programme execution.

The result is a development pathway that is more efficient, more transparent and easier to navigate.

YEARS OF OPERATION

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Years of formulation expertise across oral, nasal, pulmonary and parenteral dosage forms

employees

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Employees, scientists, manufacturing and operational staff based in Nottingham, UK

regulatory track record

MHRA

MHRA Approval in 2024 following successful initial site inspection, with a successful follow up MHRA surveillance inspection in October 2025.

growth

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MHRA Approved development and manufacturing facility for oral, nasal, pulmonary and sterile drug products.

YOUR STRATEGIC CDMO PARTNER

Partner with Upperton

Our scientific teams specialise in developing drug products that require more than conventional approaches.Whether overcoming solubility limitations, improving bioavailability, supporting novel delivery routes or managing constrained API availability, we focus on creating development strategies that give molecules the best chance of success.

One site

Award-winning facility built for scale and continuity providing integrated, end-to-end capabilities delivered under one roof.

One Team

The same team from your early-stage development through to preparation for commercial readiness.

Dosage Form Expertise

Proven track record in solving formulation and delivery challenges across multiple dosage forms.

Executive Leadership on Every Project

Direct access to experienced senior leadership for strategic oversight and decision-making.

FROM FEASIBILITY TO COMMERCIAL READINESS

Science to Move Your
Molecule Forward.

From formulation development to GMP manufacture, our integrated teams work together to solve technical challenges, reduce programme risk and accelerate progression through development.

01

Formulation Development

Developing solutions for molecules where solubility, stability or delivery challenges limit progress for small molecules and biologics.

02

Analytical Development & Validation

Generating the data, methods and quality controls needed to support confident development decisions.

03

Phase I–II Clinical Supply

Flexible GMP manufacturing and supply solutions supporting first-in-human and early clinical studies.

04

Scale Up for Phase III and Commercial Readiness

Building scalable, manufacturable processes that support successful late phase and commercial preparation.

05

Regulatory and CMC Support

Supporting your development programme with the documentation required for regulatory submissions.

Let's discuss your programme

Delivering confidence at every step

Choosing the right CDMO partner can determine the success of a development programme.

At Upperton, we combine scientific problem-solving, integrated delivery and manufacturing expertise to help sponsors navigate complexity, reduce risk and accelerate progress towards the clinic and beyond.

Speak with an Expert