After less than two weeks in our new home we are delighted to announce that our non-GMP pilot plant has come on stream and is now available for customer use.
Our newly refurbished Pilot Plant will enable us to develop processes and produce batches of spray dried powder utilising equipment identical to that housed in our new clinical trials manufacturing plant.
The Upperton Pilot Plant now houses a range of spray dryers that can process solutions at a range of scales, namely:
- Buchi B-290 (Typical batch sizes of 100mg to 50g spray dried powder)
- ProCepT 4M8 (Typical batch sizes of 100mg to 200g spray dried powder)
- Upperton Pharma Dryer (typical batch sizes of 10g to 200g spray dried powder)
- Niro PSD-1 (typical batch sizes of 20g to 2kg spray dried powder)
In addition to our range of extensive spray dryers we have also incorporated a range of additional processes to assist in dosage form development. All of these are available at pilot plant scale including;
- Blending and secondary drying of spray dried powders
- Dry and wet granulation and granule coating
- Powder densification, slugging and sieving
- Capsule filling and enteric coating
Drop us a line today to talk about our streamline service for research here
The conference will focus on how nano and materials technologies can strengthen competitiveness across all European industries.
Upperton Limited will be attending the Making Pharmaceuticals Exhibition & Conference at the Ricoh Arena, Coventry from 25-26 April 2017. We would be delighted to hear from any delegates who are interested in learning more about our services and capabilities. Find out more from the conference website
A new 4M8-Trix ProCepT spray dryer has been delivered and is now being commissioned at Upperton. It brings the number of spray dryers that we have in our laboratory and pilot plant to eleven.
A new automated Q5000 SA Dynamic Vapour Sorption analyser (TA Instruments) has been installed in Upperton’s analytical laboratory.
Nottingham, UK – 18th November, 2016 —Upperton is pleased to announce that it has acquired a Quantos MicroDosing unit that can be used to precisely fill a range of dosage forms including capsules, and devices for inhaled and nasal drug delivery. The new Quantos system is capable of dosing to an accuracy of ± 0.5mg, independent of substance characteristics, operator or environmental conditions. The system learns the characteristics of a product, with an RFID chip present in the dosing head storing all the key information on the substance used, including batch number and powder characteristics. Actual fill weights of each individual capsule or device are captured electronically and can be printed if required.
Nottingham, UK – 10th October, 2016 — Upperton is pleased to announce that it is to sponsor the 6th Annual MiBio Conference at Magdalene College, Cambridge (9th November 2016)
Nottingham, UK – 28th May, 2016 — Upperton has entered into a partnership with Quotient Clinical, the Translational Pharmaceutics® Company, to deliver a complete spray drying service for pharmaceutical and biotechnology companies seeking to develop spray dried formulations for clinical use. The partnership will see Upperton working with Quotient Clinical to supply GMP manufacturing services at Quotient within the MediCity life science innovation hub in Nottingham, UK.